Innovation by evolution: bringing new chemistry to life

نویسندگان

چکیده

Not satisfied with biology's vast catalyst repertoire, I want to create new enzyme catalysts and expand the chemistry of life. We use most powerful biological design process, evolution, optimize existing enzymes invent ones, thereby circumventing our profound ignorance how sequence encodes function. Chemistry encoded in DNA optimized by evolution enables efficient, sustainable routes important fuels chemicals. Evolution not only optimizes, it can also innovate entirely catalysts.

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ژورنال

عنوان ژورنال: Biophysical Journal

سال: 2022

ISSN: ['0006-3495', '1542-0086']

DOI: https://doi.org/10.1016/j.bpj.2021.11.1846